It turns out there is literally no targetKeanu Reeves' John Wick can’t take down, as the third installment in the super-assassin franchise sets its sights onAvengers: Endgame’s box office dominance.John Wick: Chapter 3 - Parabellumloaded up $22.6 million—including a great $5.9 million in Thursday night previews, the largest in Lionsgate history for a movie withoutTwilightorHunger Gamesin the title—on its way to a debut in the $55-58 million range. Barring a miracle,Endgamewill slide to number 2 for the weekend.

Parabellumsees Reeves return as the titular hitman for the third time, as a $14 million bounty on his head forces him to use everything at his disposal—including knives, an actual horse, and a library book—to fend off every killer in New York City. The film also starsHalle Berry,Ian McShane,Laurence Fishburne, andAsia Kate Dillon.

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Again, that’s not to sayAvengers: Endgamemovie is hurting for a profit. The massive Marvel movie, which took in another $7.3 million on its fourth Friday, is all but guaranteed to overtakeAvataron the all-time domestic box office list by the end of the weekend. Right now it sits at $748 million, compared toAvatar’s $760 million. (Star Wars: The Force Awakensstill holds the number 1 spot with $936 million.) Worldwide, gah, it’s stillsoclose;Endgamenudged its way up to $2.54 billion, knocking aggressively now at the door ofAvatar’s $2.74 billion.

Rounding out the top 3 for Friday night isDetective Pikachuwith another $6.2 million, knocking newcomerA Dog’s Journeyto fourth with $2.5 million.A Dog’s Journey, a sequel to 2017’s A Dog’s Purpose, is looking at a soft-as-fur $8.5 million premiere weekend. Fellow newcomerThe Sun Is Also a Star, directorRy Russo-Young’s romance at Warner Bros., opened in seventh on Friday night with $1.04 million, headed toward an estimated $2.6 million.

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Take a look at Friday’s numbers below and check back tomorrow to see a few more records get broken. (Numbers via Box Office Mojo)

John Wick: Chapter 3 - Parabellum

$22,670,000

Avengers: Endgame

$7,371,000

$748,765,870

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Pokemon Detective Pikachu

$6,260,000

$75,446,846

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A Dog’s Journey

$2,520,000

The Hustle

$1,813,050

$18,877,774