The CW has released the first image ofJon Cryer’s (Two and a Half Men) turn as Lex Luthor in an upcoming episode ofSupergirl. The episode, “O Brother Where Art Thou?” will debut in March, and will see Lex reaching out from prison to enlist the help of Lena (Katie McGrath), where he will do anything to get her on his side – “even if that means leveraging the life of one of her friends.”

We don’t know much more about what the episode will hold or what form the villain’s evil will take, but theArrow-verse has certainly been focusing more on Superman lore lately, particularly with its crossover event “Elseworlds.” As Lacy Baugher argued, it was more of an auditionfor a Superman seriesthan a Batwoman one.

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Though Cryer may be seen as something of an odd choice for Lex,Supergirlexecutive producersRobert RovnerandJessica Quellersaid in a statement when thecasting was first announced:

“We are enormous fans of Jon Cryer, and he was instantly our dream actor to play the iconic role of Lex Luthor. Jon is a super-talent, and the fact that he played Lenny Luthor in Superman IV brings an added layer of legacy to his casting.  We’re beyond thrilled to welcome Jon to the Supergirl family.”

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When it comes to bringing the villain to the show, Rovner and Queller added:

“We’re beyond excited to introduce iconic villain, Lex Luthor, to Supergirl and to weave him into our story this season.  We’ve talked about having Lex on the show since it’s inception and we’re excited to have him finally arrive.  We can’t wait for him to shake things up in National City and watch him go toe to toe with not only Supergirl, but his sister Lena Luthor (Katie McGrath).”

As our own Dave Trumbore wrote in that piece, “Cryer, who recently wrapped production on writer-directorJason Orley‘s feature filmBig Time AdolescenceoppositePete Davidson, is best known for his award-winning role on CBS’Two and a Half MenoppositeCharlie SheenandAngus T. Jones. This isn’t his first brush with the DC Comics universe, however, since he’s also voiced Felix Faust in animated form inJustice League Action. (Oh and yeahhe played a LuthorinSupermanIVin the Donnerverse.) Now, he’ll get to step into the (sure to be expensive) shoes of one of comics’ all-time great villains.”

Supergirlairs Sunday nights on The CW; check out the new image below: